HDAC4 and HDAC7 Promote Breast and Ovarian Cancer Cell Migration by Regulating Emt Relative Marker by Shuai Zhang in Crimson Publishers: Journal of Cancer Research Crimson Publishers_ Novel Approaches in Cancer Study Breast and ovarian cancer have been remained as a highly malignant tumor among women, posing a serious threat to women health worldwide. In this study, we were aimed to investigate the underlying mechanism of breast and ovarian cancer cell migration. Wound healing assay showed that MDA-MB-231and C13* have higher migration potential compare with MCF-7 and OV2078 cells, as well as regulated epithelial-mesenchymal transition (EMT) marker. We found that HDAC4 and HADC7 mRNA are up regulated in MDA-MB-231 and C13* cells. Moreover, target HDAC4 and HDAC7 by TSA or shRNA block MDA-MB-231an...