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Natural Killer Cells-based Immunotherapy: Novel Therapeutic Strategy to Halt Triple Negative Breast Cancer_Crimson Publishers

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Natural Killer Cells-based Immunotherapy: Novel Therapeutic Strategy to Halt Triple Negative Breast Cancer by Rana Ahmed Youness in Crimson Publishers: Journal of Cancer Research     Crimson Publishers_ Novel Approaches in Cancer Study Historically, Breast Cancer (BC) has not been considered as an immunogenic tumor, however over the past few years in particular several studies have demonstrated the significance and the high prognostic value of tumor infiltrating lymphocytes (TILs) in several solid tumors including BC [1]. It is worth mentioning that triple negative breast cancer (TNBC) tumors showed a high degree of immune infiltration when compared with hormone receptor positive subtypes. Therefore, clinicians hypothesized that the use of immunotherapy among TNBC patients specially those showing a high degree of TILs could definitely lead to better tumor responses and better eradication of the disease [2]. Moreover, proof-of-principle studies with immune-checkpo...

Lupine Publishers: Lupine Publishers | No Fact Check, Pharmaceutical ...

Lupine Publishers: Lupine Publishers | No Fact Check, Pharmaceutical ... : Lupine Publishers | Journal Of Orthopaedics Abstract The behavioral view of corporate governance has derived from the behav...

Advances of Cancer Synergic Photo-Therapy: Kinetics and Efficacy_Crimson Publishers

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Advances of Cancer Synergic Photo-Therapy: Kinetics and Efficacy by Jui-Teng Lin in Crimson Publishers: Journal of Cancer Research   Crimson Publishers_ Novel Approaches in Cancer Study The kinetics and efficacy of anti-cancer via phototherapy are reviewed. Factors influencing the cancer therapy efficiency in both photothermal therapy (PTT) and photodynamic therapy (PDT) using nanogold particles and photosensitizers (PS), respectively, are analyzed. Efficacy of cancer therapy may be enhanced by combining PTT and PDT either activated by one light or two lights. For maximum PTT/PDT synergistic efficacy, the concentration of photosensitizers and nanogold required optimization, besides the wavelength of the light matching the absorption peak of PS and nanogold, and the sequential order of PTT and PDT process. External supply of either photosensitizers or oxygen concentration will significantly improve the anti-cancer efficacy via type-II PDT. The singlet oxygen t...