Crimson Publishers- Novel Approaches in Cancer Study

Are we Still Missing the Target in Trying to Prevent and Treat Human Cancers? by James E Trosko in Journal of Cancer Research   Crimson Publishers_   Novel Approaches in Cancer Study   Solving the problem of preventing or treating cancers is still a major problem. While much is known about those multi-disciplinary contributors to the initiation, promotion and progression phases of human cancers, major hurdles to efficacious prevention and treatment involve, while recognizing that there are many known factors that can influence human carcinogenesis, little integration of this knowledge has been used. This brief “Opinion” paper hypothesizes that, by recognizing the multi-stage, multi-mechanism process of carcinogenesis, the roles of organ-specific adult stem cells as the “targets for two types of “cancer stem cells”, and new strategies for nutritional /dietary intervention, could help in the prevention of early susceptibility for cancers later in life, as well as...

Review on Gastric Cancer by Tadesse Haye in Journal of Cancer Research   Crimson Publishers_   Novel Approaches in Cancer Study   The first statistical analysis of stomach cancer incidence and mortality was in Italy, in the 18s century. Stomach cancer remains one of the leadings causes of cancer incidence and mortality globally. https://crimsonpublishers.com/nacs/fulltext/NACS.000555.php please click on the link https://www.scilit.net/publisher/9410/10350

Decreased Expression of P16 Indicates the Postoperative Poor Prognosis of Esophageal Squamous Cell Carcinoma Patients by Yufeng Cheng in Journal of Cancer Research   Crimson Publishers_   Novel Approaches in Cancer Study   Expression of P 16 gene that is the key regulatory protein of the cell cycle has been linked with the prognosis of Esophageal squamous cell carcinoma patients.   https://crimsonpublishers.com/nacs/fulltext/NACS.000554.php     

Proteomics Exploration of Chronic Lymphocytic Leukemia by Tiara Griffen in Journal of Cancer Research   Crimson Publishers_   Novel Approaches in Cancer Study Chronic Lymphocytic Leukemia (CLL) is an adult heme malignancy characterized by the presence of mature-appearing CD5 + B cells in the blood, bone marrow, and secondary lymphoid organs [1]. In the United States, there will be an estimate of 20,720 new cases and 3,930 deaths according to the American Cancer Society statistics. Symptoms include swollen lymph nodes, frequent infections, and fatigue which negatively impacts the quality of life of people affected [1]. CLL is heterogeneous in its progression and clinical outcomes. Factors that contribute to the heterogeneity include the immunoglobulin heavy chain (IGHV) status and chromosomal aberrations [2,3]. There are two subtypes of CLL: Unmutated(U-CLL) and Mutated CLL(M-CLL). 40% and 60% of patients are diagnosed with unmutated and mutated CLL. U-CLL is charac...

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