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Showing posts from February, 2020

Analysis the Role of Oxygen, Light Intensity, Threshold Dose and Efficacy Improvement of Anti-Cancer via Type-II Photodynamic Therapy_Crimson Publishers

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Analysis the Role of Oxygen, Light Intensity, Threshold Dose and Efficacy Improvement of Anti-Cancer via Type-II Photodynamic Therapy by Jui Teng Lin in in Crimson Publishers: Journal of Cancer Research   Crimson Publishers_ Novel Approaches in Cancer Study The role of oxygen, cell killing threshold dose and efficacy improvement of anti-cancer via type-II phototherapy are analyzed by both analytic formulas and numerical data. Higher initial photoinitiator (PS) concentration (C 0 ) and/or light intensity (I 0 ) has a faster efficacy, due to faster depletion of PS and oxygen concentration. Without the external oxygen supply, higher C 0 or I 0 produces more efficient singlet oxygen, resulting a higher transient efficacy, but they reach the same steady-state value when oxygen is completely depleted. With the external oxygen supply, higher efficacy (with no steady-state limitation), or lower cell viability are achieved. The overall efficacy may be enhanced by resuppl...

Parasite Subsistence of Human Cancer_Crimson Publishers

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Parasite Subsistence of Human Cancer by Sergey N Rumyantsev in in Crimson Publishers: Journal of Cancer Research     Crimson Publishers_ Novel Approaches in Cancer Study The ability of cancer to subsist in human body like a parasite is out of the mainstream of discoveries of cancer biology, pathogenesis and epidemiology. The goal of this article is to present maximally exhaustive epidemiological, clinical, genetic and immunological evidence of invasive origin and parasite subsistence of cancerous disease. The ability of cancer to invade human body and subsist in it like a parasite is out of the mainstream of discoveries of cancer biology, pathogenesis and epidemiology. The goal of this is to present maximally exhaustive epidemiological, clinical, genetic and immunological evidence of invasive origin and of parasite subsistence of cancerous disease. The investigation is grounded on a multidisciplinary integrative reassessment and reinterpretation of rele...