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Skeletal Related Events in Metastasis Breast Cancer: Case Report_Crimson Publishers

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Skeletal Related Events in Metastasis Breast Cancer: Case Report by Ayman Rasmy in Crimson Publishers :  Journal of Cancer Research   Crimson Publishers_   Novel Approaches in Cancer Study   Breast cancer is the most common malignancy distressing females in the world. The bone metastases are one of the most common site of disease dissemination. Up to 75% of stage IV Breast cancer patients developing skeletal metastases [1] metastatic bone disease can result in skeletal related events (SREs), including humoral hypercalcaemia of malignancy (HHM), pathological fractures, spinal cord compression, and pain [2]. The median time from bone metastases diagnosis to first SRE can be as short as 1.8 months, with the incidence of SREs growing considerably during the first 12 months following diagnosis [3]. This Bone metastases affect patient survival, movement, and quality of life by negative impact. The molecular mechanisms involved in the metastasis, colonization, and prolifer...