Sub-THz Spectroscopy for Fingerprinting Biological Molecules_Crimson Publishers

Sub-THz Spectroscopy for Fingerprinting Biological Molecules by T Globus in Novel Approaches in Cancer Study
Vibrates LLC-a women owned small business organized in 2007 as a spin-off from the University of Virginia, introduces completely new, patented, fast and simple method/technology and instruments (THz spectrometers) to see signatures of molecules in liquids (including body fluids). These signatures can serve as biomarkers in medicine and other bio-industry segments, which are important for early diagnosis of cancers, mental diseases, and presence of Coronaviruses, including all new varieties. The THz frequency range is important for life science applications because of the unique ability of this radiation to interact with low energy vibrations of hydrogen bonds between atoms within biological molecules. Although hydrogen bonds are very weak compared to covalent bonds (~20 times), these weak bonds determine the three-dimensional structure of DNA, RNA, and protein molecules and are vital for all processes within biological cells. Experimental studies combined with computational Molecular Dynamic simulations demonstrated the presence of vibrational modes in absorption spectra of biological materials in THz frequency range. The frequencies and intensities of these absorption features reflect the sequence and the 3D structure of biological molecules and can serve as their specific fingerprints. All biological molecules present in body fluids contribute to fingerprints. Particularly, measurement results combined with simulations have shown that microRNAs have strong sub-THz absorption features, and the medical literature indicates the importance of specific microRNAs in regulatory pathways of all cancers and infection diseases. Read more about this article: https://crimsonpublishers.com/nacs/fulltext/NACS.000660.php For more articles in Novel Approaches in Cancer Study https://crimsonpublishers.com/nacs/

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